The New SkinMedica HA5 (Hyaluronic Acid) Innovations
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Hyaluronic acid has earned its reputation as one of the most effective ingredients in skincare, but not all HA formulas are created equal. With the launch of SkinMedica’s new HA5 innovations, including updates to the iconic SkinMedica HA5 Rejuvenating Hydrator, the brand continues its reputation for what high-performance, medical-grade hydration can look like. Often referred to as the best hyaluronic acid serum, SkinMedica continues to evolve with cleaner formulations, longer-lasting hydration, and improved skin compatibility.
In this blog, we break down The New SkinMedica HA5 (Hyaluronic Acid) Innovations, featuring insights and answers from skincare expert and Aesthetician Ashley Darbonne. From what hyaluronic acid actually does for your skin to what makes the new HA5 products different, this expert-led conversation explores why SkinMedica’s latest HA5 lineup delivers advanced hydration without compromise.
Advanced Hydration Without Compromise
“Hyaluronic acid continues to be one of the most essential ingredients in modern skincare, and SkinMedica has taken this powerhouse hydrator to the next level,” shares Darbonne, “With the launch of new hyaluronic acid products and enhancements to their existing formulations, SkinMedica once again sets the standard for medical-grade hydration that supports skin health without irritation or congestion.”
To provide a deeper dive into SkinMedica’s HA5 updates, we connected with Darbonne for the following Q&A:

Q: What Is Hyaluronic Acid?
A: Hyaluronic acid (HA) is a naturally occurring sugar molecule found in the body. It functions as a humectant, meaning it attracts and retains moisture—holding up to 1,000 times its weight in water. This makes HA critical for maintaining hydration, improving skin elasticity, and supporting a healthy skin barrier.
Unlike heavier moisturizing ingredients, hyaluronic acid delivers deep hydration without adding oil, leaving the skin plumper, smoother, and more balanced.
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Q: What Are the New SkinMedica HA5 Products?
A: SkinMedica has introduced two new hyaluronic acid products while also improving their existing HA serum. The expanded line now includes an HA5 Hydrating Foaming Cleanser with Vegan Collagen and the HA5 + Hydra Collagen (HC) Water Burst Moisturizer, along with an enhanced version of their popular HA5 serum—now reformulated as HA5 + Hydra Collagen Hydrator with Vegan Collagen (HAHC).
HA5 Hydra Collagen Hydrator with Vegan Collagen
The HA5 Hydra Collagen Hydrator delivers a significant upgrade in performance. This reformulation contains twice the amount of hyaluronic acid and is infused with vegan collagen to provide immediate hydration that lasts up to 48 hours. Skin appears instantly plumper and more dewy upon application.
One of the most notable improvements is the silicone-free formula. This makes the serum safe for acne-prone skin and eliminates the pilling that occurred with the previous version. The lightweight texture layers beautifully under skincare and makeup, making it an excellent choice as a hydrating makeup primer.
HA5 Hydra Collagen Hydrating Foaming Cleanser with Vegan Collagen
The HA5 Hydra Collagen Hydrating Foaming Cleanser is formulated with amino acids and SkinMedica’s proprietary Hyaluronic Acid and Hydra Collagen Complex, which includes five forms of hyaluronic acid and hydrolyzed collagen. It delivers immediate hydration while gently cleansing the skin.
After use, skin feels soft, calm, and thoroughly clean without any tightness or dryness.
The cleanser supports the skin barrier, making it especially beneficial for dry, sensitive, compromised, or post-procedure skin. It effectively removes makeup, oil, and impurities without stripping the skin, which is essential for maintaining barrier integrity during healing and recovery.
HA5 Hydra Collagen Water Burst Moisturizer with Vegan Collagen
This moisturizer combines five forms of hyaluronic acid with vegan hydra collagen to attract and retain moisture throughout the day. These ingredients work synergistically to deliver intense hydration while maintaining a lightweight, refreshing texture.
The HA5 Hydra Collagen Water Burst Moisturizer also features SkinMedica’s Microbiome Barrier Complex with prebiotics, which helps support the skin’s natural barrier, minimize moisture loss, and defend against environmental stressors. Skin appears bouncy, dewy, and well-hydrated. Clinical results show an immediate hydration boost of up to 25%, with hydration lasting all day.

Q: What Makes These New HA5 Products Different?
A. They offer clean, skin-safe formulation. All products in the new HAHC line are free of silicones, parabens, sulfates, fragrances, and oils. This makes them safe and effective for dry, sensitive, compromised, and acne-prone skin types, as well as ideal for use alongside corrective treatments.
Q: Why Choose SkinMedica?
A. SkinMedica is a medical-grade skincare brand known for using ingredients that are backed by clinical studies. Their formulations are designed not only to improve skin appearance but also to correct and strengthen skin health at the cellular level.
Q: What Do You Love about the HA5 products?
A. As a skincare professional, I love the new HAHC line because it is truly acne-safe. Many topical acne treatments can severely dry out the skin and compromise the barrier, leading to irritation and sensitivity.
These products help restore hydration and repair skin health without clogging pores or triggering additional breakouts, making them an essential part of a balanced acne treatment regimen.
Are You Ready to Try SkinMedica?
If you’re looking for advanced hydration that truly supports skin health without irritation, congestion, or unnecessary additives, SkinMedica’s new HA5 innovations deliver on every level. With cleaner formulations, enhanced hyaluronic acid technology, and the addition of vegan collagen, these products are designed to work seamlessly with all skin types, including sensitive and acne-prone skin.
Whether you’re upgrading your daily skincare routine or supporting your skin before or after professional treatments, the HA5 collection offers clinically backed hydration you can trust.
Ready to experience the difference medical-grade hyaluronic acid can make?
Schedule a skincare consultation or stop by our Houston or San Antonio location to explore which SkinMedica HA5 product is right for your skin goals.
Ashley Darbonne

Aesthetician
Ashley Darbonne has over 12 years of experience working in a medical setting, with eight of those years spent in a med spa environment. She entered the field due to her own skin concerns and discovered a deep sense of fulfillment in helping others improve their skin health and confidence through effective, science-backed skincare.
In addition to being an Aesthetician and holding a license as a Senior Laser Technician with the State of Texas, she holds additional treatment certifications, including for IPL and SkinPen.



